AR42J Rat Pancreatic Exocrine Cell Line

Introduction

The AR42J rat pancreatic exocrine cell line is composed of epithelial-like cells isolated and purified from Wistar rat pancreatic tumor tissues by Daniel S. Longnecker et al. Upon stimulation with glucocorticoids, these cells can be induced to exhibit exocrine activity, accompanied by extensive endoplasmic reticulum (ER) remodeling. This cell line expresses insulin and glucocorticoid receptors.

Serving as a suitable host for transfection studies, OriCell™ AR42J Rat Pancreatic Exocrine Cell Line is widely utilized in various research applications, including studies on alleviating inflammatory responses in AR42J cells by inhibiting ER stress pathways, as well as investigations into the effects of microRNAs on apoptosis of rat pancreatic acinar cells.

When citing our products in academic publications, please use the following format: "OriCell™ [Product Name] + [Catalog Number], from Cyagen Biosciences."

Product Information

QC

• Pass the detection of bacteria, fungi, mycoplasma, and endotoxins.
• Verified by cell recovery viability testing.
• Verified by STR analysis.

Please refer to "COA" for details.

General Handling Principles

• Maintain strict aseptic technique. Ensure complete sterility throughout all procedures, particularly within the laminar flow hood and incubator.
• Follow standardized protocols. Adhere strictly to the product manual. Implement rigorous control over experimental variables and include appropriate parallel controls.
• Use high-quality consumables and reagents. This product requires culture vessels suitable for adherent growth, and the reuse of these vessels is not recommended. The reagents used must be validated for reliability, cell compatibility, and batch-to-batch consistency.

Warm Notice: The cryopreservation medium of this product contains DMSO, which may pose potential risks. Please handle it with care.