Min6 Mouse Pancreatic Beta Cell Line

Introduction

The Min6 mouse pancreatic beta cell line is an insulinoma cell line established by Shun-Ichi Miyazaki et al. in 1990 from a transgenic non-obese diabetic (NOD) mouse expressing the SV40 T-antigen gene. This cell line retains physiological characteristics of normal β-cells, including the production of insulin, glucagon, somatostatin, ghrelin, and SV40 T antigen, while exhibiting morphological features characteristic of pancreatic beta cells.

OriCell™ Min6 Mouse Pancreatic Beta Cell Line maintains pancreatic β-cell-specific properties during in vitro culture and is widely used in studies of diabetes, insulin secretion mechanisms, and pancreatic β-cell function.

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Product Information

QC

• Pass the detection of bacteria, fungi, mycoplasma, and endotoxins.
• Verified by cell recovery viability testing.
• Verified by STR analysis.

Please refer to "COA" for details.

General Handling Principles

• Maintain strict aseptic technique. Ensure complete sterility throughout all procedures, particularly within the laminar flow hood and incubator.
• Follow standardized protocols. Adhere strictly to the product manual. Implement rigorous control over experimental variables and include appropriate parallel controls.
• Use high-quality consumables and reagents. This product requires culture vessels suitable for adherent growth, and the reuse of these vessels is not recommended. The reagents used must be validated for reliability, cell compatibility, and batch-to-batch consistency.

Warm Notice: The cryopreservation medium of this product contains DMSO, which may pose potential risks. Please handle it with care.