About Cyagen OriCell™

Cyagen Biosciences (Guangzhou) Inc. was established in 2006. After more than a decade of development, we have become a well-known enterprise in the field of cell biology. Our brand OriCell™ focuses on the research and development of cell biology products. Our main business includes cell products (stem cells, primary cells, cell lines), cell culture reagents, imported fetal bovine serum, and cell biology technical services. OriCell™ has been committed to providing comprehensive cell biology solutions to global universities, research institutions, hospitals, CRO and CDMO companies. Our products are sold in dozens of countries and regions worldwide, with thousands of scientific publications citing OriCell™ products and services.

OriCell™ cell biology R&D team continuously explores and optimizes cell culture technologies, accumulating extensive experience in cell isolation and culture. In cell culture, OriCell™ has developed a "spatial replication" culture technology based on vast cell culture experience. This technology extracts key components from the environment during the logarithmic growth phase of cells and, after a series of purification steps, uses them as "seeds" to rapidly replicate a space suitable for high-speed cell growth in new culture vessels. This method has been shown to increase cloning efficiency by approximately 50% and shorten the growth cycle of positive clones by 30%. Meanwhile, OriCell™ operates an antibiotic-free culture process designed from years of cell culture experience, adhering to strict environmental, material and personnel management protocols to ensure a 100% antibiotic-free and contamination-free workflow.

In the field of cell technology services, OriCell™ offers stem cell isolation and identification, directed differentiation of stem cells, primary cell isolation and identification, cell testing and serum screening, and other cell-related services. These have helped thousands of researchers solve scientific challenges. OriCell™ has independently drafted dozens of stem cell research standards, which have become internationally recognized technical references.

After more than a decade of development, OriCell™ has built a large-scale and comprehensive scientific cell bank, including numerous standard cell lines, stem cells, and primary cells. Our products have served tens of thousands of customers worldwide, achieving both high market share and customer satisfaction. Upholding the corporate vision of "Creating Infinite Possibilities for Biotechnology", all our staff are committed to continuously providing high-quality products and services to researchers globally, striving to become a new benchmark in the global cell biology field.

Certificates

Our Customers

The number of service institutions attests to our excellent reputation in the industry. OriCell™ has accelerated research progress for over 3,000 research groups worldwide.

Over 13,500 Citations, Trusted by Scientists Worldwide

Citations

1. Host FSTL1 defines the impact of stem cell therapy on liver fibrosis by potentiating the early recruitment of inflammatory macrophages

Signal Transduction and Targeted Therapy doi.org/10.1038/s41392-025-02162-6 IF 40.80（2025）

2. Dynamic GelMA/DNA Dual-Network Hydrogels Promote Woven Bone Organoid Formation and Enhance Bone Regeneration

Advanced Materials doi.org/10.1002/adma.202501254 IF 27.40（2025）

Related Products: OriCell™ SD Rat Bone Marrow Mesenchymal Stem Cells (RASMX-01001), OriCell™ Complete Medium For Human Umbilical Vein Endothelial Cells (HUVEC-90012), OriCell™ Alizarin Red S Solution (ALIR-10001)

3. HLF and PPARα axis regulates metabolic‐associated fatty liver disease through extracellular vesicles derived from the intestinal microbiota

iMeta doi.org/10.1002/imt2.70022 IF 23.80（2025）

Related Products: OriCell™ Fetal Bovine Serum (Superior Quality)

4. Synthetically Engineered Bacterial Extracellular Vesicles and IL-4-Encapsulated Hydrogels Sequentially Promote Osteoporotic Fracture Repair

ACS Nano doi.org/10.1021/acsnano.5c03106 IF 15.80（2025）

5. IL-33-Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1-IGF2R Axis in Ankylosing Spondylitis

Advanced science doi.org/10.1002/advs.202500952 IF 15.80（2025）

6. Enhanced SIRT3 expression restores mitochondrial quality control mechanism to reverse osteogenic impairment in type 2 diabetes mellitus

Bone research doi.org/10.1038/s41413-024-00399-5 IF 14.30（2025）

Related Products: OriCell™ Alizarin Red S Solution (ALIR-10001)

7. Biomimetic patch with gradient-induced regeneration for tendon-bone interface to repair rotator cuff injury

Chemical Engineering Journal doi.org/10.1016/j.cej.2025.159985 IF 13.30（2025）

8. NUP62 alleviates senescence and promotes the stemness of human dental pulp stem cells via NSD2-dependent epigenetic reprogramming

International Journal of Oral Science doi.org/10.1038/s41368-025-00362-y IF 10.80（2025）

9. Diatomite-incorporated hierarchical scaffolds for osteochondral regeneration

Bioactive Materials doi.org/10.1016/j.bioactmat.2024.05.004 IF 18.90（2024）

10. Room-temperature-stable immunosuppressive nanovesicles for mitigating im‐munopathology and streamlining cardioprotection post-infarction

Chemical Engineering Journal doi.org/10.1016/j.cej.2024.157030 IF 15.30（2024）

11. Electron-donable heterojunctions with synergetic Ru-Cu pair sites for biocatalytic microenvironment modulations in inflammatory mandible defects

Nature Communications doi.org/10.1038/s41467-024-53824-y IF 14.70（2024）

12. Engineered Magneto-Piezoelectric Nanoparticles-Enhanced Scaffolds Disrupt Biofilms and Activate Oxidative Phosphorylation in Icam1+ Macrophages forInfectious Bone Defect Regeneration

ACS NANO doi.org/10.1021/acsnano.4c13562 IF 15.80（2024）