SD Rat Bone Marrow Mesenchymal Stem Cells

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Introduction

Bone marrow mesenchymal stem cells (BMSCs) are a type of multipotent stem cell residing in the bone marrow stroma. Due to their strong proliferative capacity and immunomodulatory properties, BMSCs are widely applied in tissue engineering, cell therapy, and gene therapy.

As a research hotspot, SD rat bone marrow mesenchymal stem cells are commonly used in regenerative medicine and tissue engineering, particularly in studies involving bone, cardiovascular, and nervous system disorders.

OriCell™ SD Rat Bone Marrow Mesenchymal Stem Cells are isolated from the bone marrow of healthy SD rats. These cells exhibit robust proliferation and multipotent differentiation potential, making them a valuable cell model for studying proliferation, aging, immune regulation, differentiation, and transplantation.

When citing our products in academic publications, please use the following format: "OriCell™ [Product Name] + [Catalog Number], from Cyagen Biosciences (Guangzhou) Inc."

Product Information

Name	OriCell™ SD Rat Bone Marrow Mesenchymal Stem Cells
Catalog Number	RASMX-01001
Amount of Cells	1×10⁶ cells/vial
Passage Number	P2
Storage at	Liquid Nitrogen (-196℃)

QC

Pass the detection of bacteria, fungi, mycoplasma and endotoxins.
Pass the viability examination. The viable rates is higher than 80%.
The cell doubling time is less than 72 hours.
Flow cytometry showed that CD29, CD44, CD90 are positive (>70%), while CD34, CD45, CD11b are negative (<5%).
The cells can be induced to differentiate into osteoblasts, adipocytes, chondrocytes, etc.

Please refer to "COA" for details.

General Handing Principles

Ensure that all equipment is kept clean and tidy.
Please follow the instructions.
Use suitable and reliable consumables and reagents.
Bone marrow mesenchymal stem cells have limited ability to proliferate in vitro and cannot maintain their differentiation potential for a long time. OriCell™ SD Rat Bone Marrow Mesenchymal Stem Cells can be passaged for more than 5 times and still maintain all indicators qualified. But we always recommend using lower generation cells for scientific research.
Usually the inoculation density of rat bone marrow mesenchymal stem cells is (2.5~4) ×10⁴ live cells/cm².

Warm Notice: The cryopreservation solution of this product contains DMSO, which has potential risks. Please handle it carefully.

Note: This product is intended for research use only and is not for diagnostic, therapeutic, clinical, household, or any other applications.

OriCell-RASMX-01001-User-Manual.pdf View ››

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Basic Fibroblast Growth Factor Expression is Implicated in Mesenchymal Stem Cells Response to Light-Induced Retinal Injury.
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Temporal Expression of Pelp1 during Proliferation and Osteogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells.
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Autologous bone marrow stem cell transplantation attenuates hepatocyte apoptosis in a rat model of ex vivo liver resection and liver autotransplantation.
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Matrix metalloproteinase-9 is up-regulated by CCL19/CCR7 interaction via PI3K/Akt pathway and is involved in CCL19-driven BMSCs migration.
Biochem Biophys Res Commun 451:222 (2014) IF = 2.297 　Year 2014
Over-expression of MicroRNA-124 using a Lentiviral Vector Regulates Neurogenesis of Bone Marrow-Derived Mesenchymal Stem Cells.
Neural Regeneration Research -2014 IF = 0.22 　Year 2014
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Nanoparticle-enhanced generation of gene-transfected mesenchymal stem cells for in vivo cardiac repair.
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Enhanced hepatic differentiation of rat bone marrow-derived mesenchymal stem cells in spheroidal aggregate culture on a decellularized liver scaffold.
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Laminin-521 Promotes Rat Bone Marrow Mesenchymal Stem Cell Sheet Formation on Light-induced Cell Sheet Technology.
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The Vascular Endothelial Growth Factors-Expressing Character of Mesenchymal Stem Cells Plays a Positive Role in Treatment of Acute Lung Injury In Vivo.
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Fibroblast Growth Factor-10 (FGF-10) Mobilizes Lung-resident Mesenchymal Stem Cells and Protects Against Acute Lung Injury.
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Lentiviral vector-mediated co-overexpression of VEGF and Bcl-2 improves mesenchymal stem cell survival and enhances paracrine effects in vitro.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 40:418-426 (2017) IF = 2.341 　Year 2017
Construction of a general albumin promoter reporter system for real‑time monitoring of the differentiation status of functional hepatocytes from stem cells in mouse, rat and human.
Biomed Rep 6:627-632 (2017) 　Year 2017
MicroRNA expression analysis during FK506-induced osteogenic differentiation in rat bone marrow stromal cells.
Mol Med Rep 581-590 (2017) IF = 1.922 　Year 2017
The SDF-1/CXCR4/AKT signaling regulates bone marrow mesenchymal stem cell trafficking to promote airway remodeling in asthmatic rats.
Int J Clin Exp Med 10 (1):507-515 (2017) IF = 1.069 　Year 2017
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miR-134 inhibits chondrogenic differentiation of bone marrow mesenchymal stem cells by targeting SMAD6.
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MicroRNA-145 engineered bone marrowderived mesenchymal stem cells alleviated erectile dysfunction in aged rats.
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Complete Medium For Rat Bone Marrow Mesenchymal Stem Cells

Complete Medium For Rat Bone Marrow Mesenchymal Stem Cells (Without EXO)

Osteogenic Differentiation Medium For Rat Bone Marrow Mesenchymal Stem Cells

Adipogenic Differentiation Medium For Rat Bone Marrow Mesenchymal Stem Cells

Chondrogenic Differentiation Medium For Rat Bone Marrow Mesenchymal Stem Cells

SD Rat Bone Marrow Mesenchymal Stem Cells With GFP

SD Rat Bone Marrow Mesenchymal Stem Cells With RFP

SD Rat Bone Marrow Mesenchymal Stem Cell Exosomes

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