Wistar Rat Bone Marrow Mesenchymal Stem Cells
Introduction
Bone marrow mesenchymal stem cells (BMSCs) are a type of multipotent stem cell residing in the bone marrow stroma. Due to their strong proliferative capacity and immunomodulatory properties, BMSCs are widely applied in tissue engineering, cell therapy, and gene therapy.
As a research hotspot, Wistar rat bone marrow mesenchymal stem cells are commonly used in regenerative medicine and tissue engineering, particularly in studies involving bone, cardiovascular, and nervous system disorders.
OriCell™ Wistar Rat Bone Marrow Mesenchymal Stem Cells are isolated from the bone marrow of healthy Wistar rats. These cells exhibit robust proliferation and multipotent differentiation potential, making them a valuable cell model for studying proliferation, aging, immune regulation, differentiation, and transplantation.
When citing our products in academic journals, please indicate "OriCell™ + Catalog Number, from Cyagen Biosciences (Guangzhou) Inc."
Product Information
| Name | OriCell™ Wistar Rat Bone Marrow Mesenchymal Stem Cells |
| Catalog Number | RAWMX-01001 |
| Amount of Cells | 1×106 cells/vial |
| Passage Number | P2 |
| Storage at | Liquid Nitrogen (-196℃) |
QC
- Pass the detection of bacteria, fungi, mycoplasma and endotoxins.
- Pass the viability examination. The viable rates is higher than 80%.
- The cell doubling time is less than 72 hours.
- Flow cytometry showed that CD29, CD44, CD90 are positive (>70%), while CD34, CD45, CD11b are negative (<5%).
- The cells can be induced to differentiate into osteoblasts, adipocytes, chondrocytes, etc.
Please refer to "COA" for details.
General Handing Principles
- Ensure that all equipment is kept clean and tidy.
- Please follow the instructions.
- Use suitable and reliable consumables and reagents.
- Bone marrow mesenchymal stem cells have limited ability to proliferate in vitro and cannot maintain their differentiation potential for a long time. OriCell™ Wistar Rat Bone Marrow Mesenchymal Stem Cells can be passaged for more than 5 times and still maintain all indicators qualified. But we always recommend using lower generation cells for scientific research.
- Usually the inoculation density of rat bone marrow mesenchymal stem cells is (2.5~4) ×104 live cells/cm2.
Warm Notice: The cryopreservation solution of this product contains DMSO, which has potential risks. Please handle it carefully.
- Differential Clearance of Rat and Human Bone Marrow-Derived Mesenchymal Stem Cells From the Brain After Intra-arterial Infusion in Rats. 点击索取文献 ››
- The cerebral embolism evoked by intra-arterial delivery of allogeneic bone marrow mesenchymal stem cells in rats is related to cell dose and infusion velocity. 点击索取文献 ››
- Primed Mesenchymal Stem Cells Alter and Improve Rat Medial Collateral Ligament Healing. 点击索取文献 ››
- An inhibitory role of osthole in rat MSCs osteogenic differentiation and proliferation via wnt-β-catenin and Erk1-2-MAPK pathways. 点击索取文献 ››
- Clumping and Viability of Bone Marrow Derived Mesenchymal Stromal Cells under Different Preparation Procedures A Flow Cytometry-Based In Vitro Study. 点击索取文献 ››
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Differential Clearance of Rat and Human Bone Marrow-Derived Mesenchymal Stem Cells From the Brain After Intra-arterial Infusion in Rats.
Cell Transplant 24:819 (2015) Year 2015
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The cerebral embolism evoked by intra-arterial delivery of allogeneic bone marrow mesenchymal stem cells in rats is related to cell dose and infusion velocity.
Stem Cell Res Ther PMID:25971703 (2015) IF = 4.963 Year 2015
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Primed Mesenchymal Stem Cells Alter and Improve Rat Medial Collateral Ligament Healing.
Stem Cell Rev PMID:26530282 (2015) IF = 2.768 Year 2015
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An inhibitory role of osthole in rat MSCs osteogenic differentiation and proliferation via wnt-β-catenin and Erk1-2-MAPK pathways.
Cell Physiol Biochem 38:2375 (2016) IF = 4.652 Year 2016
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Clumping and Viability of Bone Marrow Derived Mesenchymal Stromal Cells under Different Preparation Procedures A Flow Cytometry-Based In Vitro Study.
Stem Cells Int 27022399 (2016) IF = 3.687 Year 2016