MC38 Mouse Colon Cancer Cell Line

Introduction

The MC38 mouse colon cancer cell line was derived from colon tumor tissue of C57BL/6 mice that had been chronically exposed to the carcinogen DMH (1,2-dimethylhydrazine dihydrochloride). MC38 cells exhibit epithelial-like morphology, grow adherently, and are capable of forming subcutaneous tumors.

MC38 is commonly used in colon cancer research. When implanted into C57BL/6 mice or immunodeficient mice, MC38 cells form tumors and can metastasize, making them widely used for studies on colorectal cancer initiation and metastasis.

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Product Information

QC

• Pass the detection of bacteria, fungi, mycoplasma, and endotoxins.
• Verified by cell recovery viability testing.
• Verified by STR analysis.

Please refer to "COA" for details.

General Handling Principles

• Maintain strict aseptic technique. Ensure complete sterility throughout all procedures, particularly within the laminar flow hood and incubator.
• Follow standardized protocols. Adhere strictly to the product manual. Implement rigorous control over experimental variables and include appropriate parallel controls.
• Use high-quality consumables and reagents. This product requires culture vessels suitable for adherent growth, and the reuse of these vessels is not recommended. The reagents used must be validated for reliability, cell compatibility, and batch-to-batch consistency.

Warm Notice: The cryopreservation medium of this product contains DMSO, which may pose potential risks. Please handle it with care.