YAC-1 Mouse Lymphoma Cell Line

Introduction

OriCell™ YAC-1 Mouse Lymphoma Cell Line is a murine lymphoma cell line induced by the Moloney Leukemia Virus (MLV) in newborn A/Sn mice. It exhibits lymphoblast-like morphology and grows primarily in suspension or semi-suspension, with minimal adherence. The cell line proliferates rapidly with a doubling time of approximately 12 to 24 hours, facilitating large-scale expansion for standardized assays.

Due to its high sensitivity to natural killer (NK) cell-mediated cytotoxicity, the YAC-1 cell line is widely used as a gold-standard target cell for murine NK cell activity assays. It serves as an essential tool in lymphoma-related research, including the pharmacological screening of chemotherapeutic agents and studies on the therapeutic effects of traditional medicines, such as Shijiaocao Kechuan tablets.

When citing our products in academic publications, please use the following format: "OriCell™ [Product Name] + [Catalog Number], from Cyagen Biosciences.”

Product Information

QC

• Pass the detection of bacteria, fungi, mycoplasma, and endotoxins.
• Verified by cell recovery viability testing, with a post-thaw survival rate >90%.
• Verified by STR analysis.

Please refer to "COA" for details.

General Handling Principles

• Maintain strict aseptic technique. Ensure complete sterility throughout all procedures, particularly within the laminar flow hood and incubator.
• Follow standardized protocols. Adhere strictly to the product manual. Implement rigorous control over experimental variables and include appropriate parallel controls.
• Use high-quality consumables and reagents. This product requires culture vessels suitable for suspension growth, and the reuse of these vessels is not recommended. The reagents used must be validated for reliability, cell compatibility, and batch-to-batch consistency.

Warm Notice: The cryopreservation medium of this product contains DMSO, which may pose potential risks. Please handle it with care.