Neuro-2a Mouse Neuroblastoma Cell Line

Introduction

The Neuro-2a mouse neuroblastoma cell line was established by R. J. Klebe and F. H. Ruddle from a spontaneous tumor in strain A albino mice. This cell line produces large amounts of tubulin, a protein that functions as part of the contractile system responsible for axoplasmic transport in neurons.

OriCell™ Neuro-2a Mouse Neuroblastoma Cell Line is widely used to study the mechanism of vinblastine-induced tubulin precipitation, the kinetics of GTP binding to isolated proteins, the turnover of microtubules in vivo, and the synthesis and assembly of tubulin. The World Organisation for Animal Health (WOAH, formerly OIE) uses this cell line for the routine diagnosis of rabies.

When citing our products in academic publications, please use the following format: "OriCell™ [Product Name] + [Catalog Number], from Cyagen Biosciences."

Product Information

QC

• Pass the detection of bacteria, fungi, mycoplasma, and endotoxins.
• Verified by cell recovery testing, with a post-thaw viability of >90%.
• Verified by STR analysis.

Please refer to "COA" for details.

General Handling Principles

• Maintain strict aseptic technique. Ensure complete sterility throughout all procedures, particularly within the laminar flow hood and incubator.
• Follow standardized protocols. Adhere strictly to the product manual. Implement rigorous control over experimental variables and include appropriate parallel controls.
• Use high-quality consumables and reagents. This product requires culture vessels suitable for adherent growth, and the reuse of these vessels is not recommended. The reagents used must be validated for reliability, cell compatibility, and batch-to-batch consistency.

Warm Notice: The cryopreservation medium of this product contains DMSO, which may pose potential risks. Please handle it with care.