ATDC-5 Mouse Chondrogenic Cell Line

Introduction

The ATDC5 mouse chondrogenic cell line was established in 1989 by Atsuchi et al. It was isolated from differentiated cultures of the AT805 teratocarcinoma, which originated from male 129 strain mouse embryos. Its parental cell line is AT805. The ATDC5 cell line is one of the most important and widely used in vitro models in the fields of cartilage biology and skeletal development research.

OriCell™ ATDC-5 Mouse Chondrogenic Cell Line is mainly used to investigate the key signaling pathways regulating chondrocyte differentiation, including the roles of BMP, TGF-β, Wnt, IHH/PTHrP, and FGF signaling pathways in this process.

When citing our products in academic publications, please use the following format: "OriCell™ [Product Name] + [Catalog Number], from Cyagen Biosciences."

Product Information

QC

• Pass the detection of bacteria, fungi, mycoplasma, and endotoxins.
• Verified by cell recovery viability testing.
• Verified by STR analysis.

Please refer to "COA" for details.

General Handling Principles

• Maintain strict aseptic technique. Ensure complete sterility throughout all procedures, particularly within the laminar flow hood and incubator.
• Follow standardized protocols. Adhere strictly to the product manual. Implement rigorous control over experimental variables and include appropriate parallel controls.
• Use high-quality consumables and reagents. This product requires culture vessels suitable for adherent growth, and the reuse of these vessels is not recommended. The reagents used must be validated for reliability, cell compatibility, and batch-to-batch consistency.

Warm Notice: The cryopreservation medium of this product contains DMSO, which may pose potential risks. Please handle it with care.